Ultrastructure of prostatic benign hyperplasia and carcinoma

Akhouri A Sinha, Clyde E. Blackard

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Prostatic tissue from 39 patients was examined by light and electron microscopy, and adenocarcinoma was demonstrated in 25 patients, benign prostatic hyperplasia in 9, and prostatitis in 5. By utilizing ultrastructural features characteristic of each condition, carcinomatous cells and acini could be distinguished from benign prostatic hyperplasia even in well-differentiated cancers. In some sections, fine structural changes characteristic of carcinoma were noted even though histologic changes of carcinoma were not observed. These sections were cut from blocks adjacent to areas of histologic carcinoma and from benign prostatic hyperplasia.

Original languageEnglish (US)
Pages (from-to)114-120
Number of pages7
Issue number2
StatePublished - Aug 1973

Bibliographical note

Funding Information:
*Supported in part by U.S. Public Health Service grant AM-11376 and National Institutes of Health grant 69-2136.


Dive into the research topics of 'Ultrastructure of prostatic benign hyperplasia and carcinoma'. Together they form a unique fingerprint.

Cite this