Ultrahigh field and ultrahigh resolution fMRI

Functional magnetic resonance imaging (fMRI) has become one of the most powerful tools for investigating the human brain. Ultrahigh magnetic field (UHF) of 7 Tesla has played a critical role in enabling higher resolution and more accurate (relative to the neuronal activity) functional maps. However, even with these gains, the fMRI approach is challenged relative to the spatial scale over which brain function is organized. Therefore, going forward, significant advances in fMRI are still needed. Such advances will predominantly come from magnetic fields significantly higher than 7 Tesla, which is the most commonly used UHF platform today, and additional technologies that will include developments in pulse sequences, image reconstruction, noise suppression, and image analysis in order to further enhance and augment the gains than can be realized by going to higher magnetic fields.