Ultra-High-Field Imaging of the Pediatric Brain and Spinal Cord

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Neuroimaging with ultra-high field magnets (≥7T) provides superior signal-to-noise, spatial resolution and tissue contrast; but also greater safety concerns, longer scanning times, and increased distortion and field inhomogeneity. Brain and spinal cord anatomic microstructure and function imaged in greater detail offers improved lesion detection, delineation, and characterization. The ongoing development of novel imaging contrasts and translation of cutting-edge sequences will aid more accurate, sensitive, and precise diagnosis, interventional planning, and follow-up for a variety of pathologic conditions.

Original languageEnglish (US)
Pages (from-to)643-653
Number of pages11
JournalMagnetic Resonance Imaging Clinics of North America
Volume29
Issue number4
DOIs
StatePublished - Nov 2021

Bibliographical note

Funding Information:
I. Nestrasil was supported by the Million Dollar Bike Ride from the University of Pennsylvania , PA, USA (MDBR-17–123-MPS; 303052MPS1-16–003–02); Sanofi Genzyme, Cambridge, MA, USA (GZ-2014-11270), and National MPS Society (project #00067088).

Funding Information:
I. Nestrasil was supported by the Million Dollar Bike Ride from the University of Pennsylvania, PA, USA (MDBR-17?123-MPS; 303052MPS1-16?003?02); Sanofi Genzyme, Cambridge, MA, USA (GZ-2014-11270), and National MPS Society (project #00067088).The authors thank Prof. G?lin ?z (CMRR, University of Minnesota) for providing the ALD proton MR spectra in Fig. 1. D.K. Deelchand has nothing to disclose. M.L. Ho is principal investigator on the Radiological Society of North America Research Scholar Grant, Society for Pediatric Radiology Pilot Award, and American Society of Head and Neck Radiology William N. Hanafee Award, for work unrelated to this article. I. Nestrasil is consultant for ICON and Quantims; received research support from National MPS Society, Sanofi Genzyme, Biomarin, and Shire/Takeda.

Keywords

  • 7T
  • Brain
  • High field
  • MR spectroscopy
  • Pediatric
  • Spinal cord
  • Ultra-high-field
  • Neuroimaging
  • Humans
  • Spinal Cord/diagnostic imaging
  • Brain/diagnostic imaging
  • Magnetic Resonance Imaging
  • Child

PubMed: MeSH publication types

  • Review
  • Journal Article

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