Abstract
Neuroimaging with ultra-high field magnets (≥7T) provides superior signal-to-noise, spatial resolution and tissue contrast; but also greater safety concerns, longer scanning times, and increased distortion and field inhomogeneity. Brain and spinal cord anatomic microstructure and function imaged in greater detail offers improved lesion detection, delineation, and characterization. The ongoing development of novel imaging contrasts and translation of cutting-edge sequences will aid more accurate, sensitive, and precise diagnosis, interventional planning, and follow-up for a variety of pathologic conditions.
Original language | English (US) |
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Pages (from-to) | 643-653 |
Number of pages | 11 |
Journal | Magnetic Resonance Imaging Clinics of North America |
Volume | 29 |
Issue number | 4 |
DOIs | |
State | Published - Nov 2021 |
Bibliographical note
Funding Information:I. Nestrasil was supported by the Million Dollar Bike Ride from the University of Pennsylvania , PA, USA (MDBR-17–123-MPS; 303052MPS1-16–003–02); Sanofi Genzyme, Cambridge, MA, USA (GZ-2014-11270), and National MPS Society (project #00067088).
Funding Information:
I. Nestrasil was supported by the Million Dollar Bike Ride from the University of Pennsylvania, PA, USA (MDBR-17?123-MPS; 303052MPS1-16?003?02); Sanofi Genzyme, Cambridge, MA, USA (GZ-2014-11270), and National MPS Society (project #00067088).The authors thank Prof. G?lin ?z (CMRR, University of Minnesota) for providing the ALD proton MR spectra in Fig. 1. D.K. Deelchand has nothing to disclose. M.L. Ho is principal investigator on the Radiological Society of North America Research Scholar Grant, Society for Pediatric Radiology Pilot Award, and American Society of Head and Neck Radiology William N. Hanafee Award, for work unrelated to this article. I. Nestrasil is consultant for ICON and Quantims; received research support from National MPS Society, Sanofi Genzyme, Biomarin, and Shire/Takeda.
Keywords
- 7T
- Brain
- High field
- MR spectroscopy
- Pediatric
- Spinal cord
- Ultra-high-field
- Neuroimaging
- Humans
- Spinal Cord/diagnostic imaging
- Brain/diagnostic imaging
- Magnetic Resonance Imaging
- Child
Center for Magnetic Resonance Research (CMRR) tags
- MRE
PubMed: MeSH publication types
- Review
- Journal Article