Type I insulin-like growth factor receptor as a therapeutic target in cancer

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Abstract

Data from experimental model systems and population studies have implicated type I insulin-like growth factor receptor (IGF1R) signaling in many different human cancers. Drugs to disrupt IGF1R function have been developed and are now entering clinical trial. This brief review will identify key areas to consider as these clinical trials move forward.

Original languageEnglish (US)
Pages (from-to)10123-10127
Number of pages5
JournalCancer Research
Volume65
Issue number22
DOIs
StatePublished - Nov 15 2005

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