Abstract
In this tutorial, we discuss the motivations for doing two-dimensional liquid chromatography (2DLC) and describe the commonly used implementations of the method. We review important guiding principles for method development, discuss the state of the art in 2D-LC performance as measured by peak capacity, and describe example applications from different fields that we hope will inspire new users to adopt 2D-LC for their analytical problems.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 519-531 |
| Number of pages | 13 |
| Journal | Analytical Chemistry |
| Volume | 89 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 3 2017 |
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