Trophoblastic microemboli as a marker for preeclampsia-eclampsia in sudden unexpected maternal death: A case report and review of the literature

Andrew M. Baker, Mitchel K. Morey, Kathryn K. Berg, John Crosson

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

The authors report the case of a 25-year-old white woman at 7 months' gestation who died suddenly and unexpectedly at home. Anatomic findings at autopsy included a tongue contusion, glomerulonephritis, changes indicative of systemic hypertension, and trophoblastic microemboli in the lungs. Review of the prenatal care record disclosed 3+ proteinuria 2 days before death. The features of the postmortem examination were consistent with clinically undiagnosed preeclampsia-eclampsia and glomerulonephritis. The authors discuss the rarity of fatal preeclampsia-eclampsia, the contribution of concomitant glomerulonephritis, and the significance of trophoblastic microemboli in the lungs.

Original languageEnglish (US)
Pages (from-to)354-358
Number of pages5
JournalAmerican Journal of Forensic Medicine and Pathology
Volume21
Issue number4
DOIs
StatePublished - Dec 6 2000

Keywords

  • Eclampsia
  • Emboli
  • Glomerulonephritis
  • Preeclampsia
  • Pregnancy
  • Sudden death
  • Trophoblast

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