Triple-bonded unsaturated fatty acids are redox active compounds

Douglas A. Peterson; Helen L. Reeve; Daniel Nelson; Stephen L. Archer; E. Kenneth Weir

doi:10.1007/s11745-001-0740-6

Triple-bonded unsaturated fatty acids are redox active compounds

Douglas A. Peterson, Helen L. Reeve, Daniel Nelson, Stephen L. Archer, E. Kenneth Weir

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Unsaturated fatty acids with triple bonds are used as inhibitors of unsaturated fatty acid metabolism or cytochrome P450 reactions because they are believed to be chemically inert. In this paper we use in vitro cytochrome C reduction to show that two commonly used triple-bonded unsaturated fatty acids are in fact potent electron transfer agents and could affect the multiple cellular systems that are redox-modulated.

Original language	English (US)
Pages (from-to)	431-433
Number of pages	3
Journal	Lipids
Volume	36
Issue number	4
DOIs	https://doi.org/10.1007/s11745-001-0740-6
State	Published - 2001

Bibliographical note

Funding Information:
These studies were supported by VA Merit Review funds. H.L. Reeve is supported by NHLBI grant R29-HL-59182-01 and S.L. Archer by the Medical Research Council of Canada, the Heart & Stroke Foundation of Canada, and the Alberta Heritage Foundation for Medical Research.

Publisher link

10.1007/s11745-001-0740-6

Find It

Find It at U of M Libraries

Cite this

@article{2b7bdbec602343b29713a409c234aba7,

title = "Triple-bonded unsaturated fatty acids are redox active compounds",

abstract = "Unsaturated fatty acids with triple bonds are used as inhibitors of unsaturated fatty acid metabolism or cytochrome P450 reactions because they are believed to be chemically inert. In this paper we use in vitro cytochrome C reduction to show that two commonly used triple-bonded unsaturated fatty acids are in fact potent electron transfer agents and could affect the multiple cellular systems that are redox-modulated.",

author = "Peterson, {Douglas A.} and Reeve, {Helen L.} and Daniel Nelson and Archer, {Stephen L.} and Weir, {E. Kenneth}",

note = "Funding Information: These studies were supported by VA Merit Review funds. H.L. Reeve is supported by NHLBI grant R29-HL-59182-01 and S.L. Archer by the Medical Research Council of Canada, the Heart & Stroke Foundation of Canada, and the Alberta Heritage Foundation for Medical Research.",

year = "2001",

doi = "10.1007/s11745-001-0740-6",

language = "English (US)",

volume = "36",

pages = "431--433",

journal = "Lipids",

issn = "0024-4201",

publisher = "John Wiley & Sons Inc.",

number = "4",

}

TY - JOUR

T1 - Triple-bonded unsaturated fatty acids are redox active compounds

AU - Peterson, Douglas A.

AU - Reeve, Helen L.

AU - Nelson, Daniel

AU - Archer, Stephen L.

AU - Weir, E. Kenneth

N1 - Funding Information: These studies were supported by VA Merit Review funds. H.L. Reeve is supported by NHLBI grant R29-HL-59182-01 and S.L. Archer by the Medical Research Council of Canada, the Heart & Stroke Foundation of Canada, and the Alberta Heritage Foundation for Medical Research.

PY - 2001

Y1 - 2001

N2 - Unsaturated fatty acids with triple bonds are used as inhibitors of unsaturated fatty acid metabolism or cytochrome P450 reactions because they are believed to be chemically inert. In this paper we use in vitro cytochrome C reduction to show that two commonly used triple-bonded unsaturated fatty acids are in fact potent electron transfer agents and could affect the multiple cellular systems that are redox-modulated.

AB - Unsaturated fatty acids with triple bonds are used as inhibitors of unsaturated fatty acid metabolism or cytochrome P450 reactions because they are believed to be chemically inert. In this paper we use in vitro cytochrome C reduction to show that two commonly used triple-bonded unsaturated fatty acids are in fact potent electron transfer agents and could affect the multiple cellular systems that are redox-modulated.

UR - http://www.scopus.com/inward/record.url?scp=0035041486&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035041486&partnerID=8YFLogxK

U2 - 10.1007/s11745-001-0740-6

DO - 10.1007/s11745-001-0740-6

M3 - Article

C2 - 11383698

AN - SCOPUS:0035041486

SN - 0024-4201

VL - 36

SP - 431

EP - 433

JO - Lipids

JF - Lipids

IS - 4

ER -

Triple-bonded unsaturated fatty acids are redox active compounds

Abstract

Bibliographical note

Publisher link

Find It

Other files and links

Fingerprint

Cite this