TY - JOUR
T1 - TrichOME
T2 - A comparative omics database for plant trichomes
AU - Dai, Xinbin
AU - Wang, Guodong
AU - Yang, Dong Sik
AU - Tang, Yuhong
AU - Broun, Pierre
AU - Marks, M. David
AU - Sumner, Lloyd W.
AU - Dixon, Richard A.
AU - Zhao, Patrick Xuechun
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2010/1
Y1 - 2010/1
N2 - Plant secretory trichomes have a unique capacity for chemical synthesis and secretion and have been described as biofactories for the production of natural products. However, until recently, most trichome-specific metabolic pathways and genes involved in various trichome developmental stages have remained unknown. Furthermore, only a very limited amount of plant trichome genomics information is available in scattered databases. We present an integrated "omics" database, TrichOME, to facilitate the study of plant trichomes. The database hosts a large volume of functional omics data, including expressed sequence tag/unigene sequences, microarray hybridizations from both trichome and control tissues, mass spectrometry-based trichome metabolite profiles, and trichome-related genes curated from published literature. The expressed sequence tag/ unigene sequences have been annotated based upon sequence similarity with popular databases (e.g. Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and Transporter Classification Database). The unigenes, metabolites, curated genes, and probe sets have been mapped against each other to enable comparative analysis. The database also integrates bioinformatics tools with a focus on the mining of trichome-specific genes in unigenes and microarray-based gene expression profiles. TrichOME is a http://www.planttrichome.org.
AB - Plant secretory trichomes have a unique capacity for chemical synthesis and secretion and have been described as biofactories for the production of natural products. However, until recently, most trichome-specific metabolic pathways and genes involved in various trichome developmental stages have remained unknown. Furthermore, only a very limited amount of plant trichome genomics information is available in scattered databases. We present an integrated "omics" database, TrichOME, to facilitate the study of plant trichomes. The database hosts a large volume of functional omics data, including expressed sequence tag/unigene sequences, microarray hybridizations from both trichome and control tissues, mass spectrometry-based trichome metabolite profiles, and trichome-related genes curated from published literature. The expressed sequence tag/ unigene sequences have been annotated based upon sequence similarity with popular databases (e.g. Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and Transporter Classification Database). The unigenes, metabolites, curated genes, and probe sets have been mapped against each other to enable comparative analysis. The database also integrates bioinformatics tools with a focus on the mining of trichome-specific genes in unigenes and microarray-based gene expression profiles. TrichOME is a http://www.planttrichome.org.
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U2 - 10.1104/pp.109.145813
DO - 10.1104/pp.109.145813
M3 - Article
C2 - 19939948
AN - SCOPUS:73249117059
VL - 152
SP - 44
EP - 54
JO - Plant Physiology
JF - Plant Physiology
SN - 0032-0889
IS - 1
ER -