Triazole-estradiol analogs: A potential cancer therapeutic targeting ovarian and colorectal cancer

Keyphrases

• 1,2,3-triazole 50%
• Active Compounds 50%
• Active Systems 50%
• ATP-binding Cassette Transporter A1 (ABCA1) 50%
• Biologically Active 50%
• Cancer Inhibition 50%
• Cancer Therapeutics 100%
• Cell Viability 50%
• Colorectal Cancer 100%
• Colorectal Cancer Cell Lines 50%
• Drug Delivery System 50%
• Drug Efflux 50%
• Drug Resistance 100%
• Efflux Proteins 50%
• EGFR Pathway 50%
• Epidermal Growth Factor Receptor 50%
• Estradiol 100%
• Estradiol Analog 100%
• G1 Phase 50%
• HT-29 50%
• In Cancer 50%
• Inhibition Resistance 50%
• Inhibition Studies 50%
• Mammalian Target of Rapamycin (mTOR) 50%
• Mechanism of Action Studies 50%
• Mitogen-activated Protein Kinase 50%
• Modeling Approach 50%
• Molecular Modeling 50%
• Molecular Targets 50%
• Ovarian Cancer 100%
• Ovarian Cancer Cells 50%
• P-glycoprotein (P-gp) 50%
• Pharmacophore 50%
• Potential Treatments 50%
• Protein Drug 50%
• Protein Inhibition 50%
• Steroid Skeleton 50%
• Target Molecule 50%
• Therapeutic Targeting 100%
• Treatment Options 50%
• Triazole 100%
• Triazole Analogues 100%

Pharmacology, Toxicology and Pharmaceutical Science

• ABC Transporter 33%
• Cancer Inhibition 33%
• Cell Viability 33%
• Colorectal Carcinoma 100%
• Diethylstilbestrol 100%
• Drug Delivery System 33%
• Drug Resistance 66%
• Effusion 33%
• Epidermal Growth Factor Receptor 100%
• Malignant Neoplasm 100%
• Mitogen Activated Protein Kinase 33%
• Molecular Target 33%
• Ovary Cancer 33%
• P-Glycoprotein 33%
• Triazole 100%
• Triazole Derivative 33%