Abstract
In this issue of Blood, Bastien and colleagues demonstrate that photopheresis purges donor T cells proliferating against host alloantigens in patients with GVHD after HSCT.1 Photodepletion of these alloreactive lymphocytes concomitantly preserves and expands Tregs, which when reinfused into patients with treatment-refractory chronic GVHD, survive in vivo and correlate with positive clinical responses.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4736-4737 |
| Number of pages | 2 |
| Journal | Blood |
| Volume | 116 |
| Issue number | 23 |
| DOIs |
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| State | Published - Dec 2 2010 |
| Externally published | Yes |