Treatment of spinocerebellar ataxia with buspirone

Mitra Assadi; Joseph V. Campellone; Christopher G. Janson; J. Jon Veloski; Robert J. Schwartzman; Paola Leone

doi:10.1016/j.jns.2007.04.019

Treatment of spinocerebellar ataxia with buspirone

Mitra Assadi
, Joseph V. Campellone
, Christopher G. Janson
, J. Jon Veloski
, Robert J. Schwartzman
, Paola Leone

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Preliminary data suggest potential benefit of 5-HT receptor agonists in the treatment of ataxias. We studied the effects of buspirone in a cohort of twenty patients with spinocerebellar ataxia (SCA). Twenty patients were treated in this double-blind, placebo controlled, cross-over trial with either buspirone HCl 30 mg twice daily or placebo for 3 months. Buspirone was not shown to be superior to placebo in the treatment of patients with SCA.

Original language	English (US)
Pages (from-to)	143-146
Number of pages	4
Journal	Journal of the Neurological Sciences
Volume	260
Issue number	1-2
DOIs	https://doi.org/10.1016/j.jns.2007.04.019
State	Published - Sep 15 2007
Externally published	Yes

Keywords

Ataxia
Buspirone
SCA

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10.1016/j.jns.2007.04.019

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title = "Treatment of spinocerebellar ataxia with buspirone",

abstract = "Preliminary data suggest potential benefit of 5-HT receptor agonists in the treatment of ataxias. We studied the effects of buspirone in a cohort of twenty patients with spinocerebellar ataxia (SCA). Twenty patients were treated in this double-blind, placebo controlled, cross-over trial with either buspirone HCl 30 mg twice daily or placebo for 3 months. Buspirone was not shown to be superior to placebo in the treatment of patients with SCA.",

keywords = "Ataxia, Buspirone, SCA",

author = "Mitra Assadi and Campellone, \{Joseph V.\} and Janson, \{Christopher G.\} and Veloski, \{J. Jon\} and Schwartzman, \{Robert J.\} and Paola Leone",

year = "2007",

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day = "15",

doi = "10.1016/j.jns.2007.04.019",

language = "English (US)",

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TY - JOUR

T1 - Treatment of spinocerebellar ataxia with buspirone

AU - Assadi, Mitra

AU - Campellone, Joseph V.

AU - Janson, Christopher G.

AU - Veloski, J. Jon

AU - Schwartzman, Robert J.

AU - Leone, Paola

PY - 2007/9/15

Y1 - 2007/9/15

N2 - Preliminary data suggest potential benefit of 5-HT receptor agonists in the treatment of ataxias. We studied the effects of buspirone in a cohort of twenty patients with spinocerebellar ataxia (SCA). Twenty patients were treated in this double-blind, placebo controlled, cross-over trial with either buspirone HCl 30 mg twice daily or placebo for 3 months. Buspirone was not shown to be superior to placebo in the treatment of patients with SCA.

AB - Preliminary data suggest potential benefit of 5-HT receptor agonists in the treatment of ataxias. We studied the effects of buspirone in a cohort of twenty patients with spinocerebellar ataxia (SCA). Twenty patients were treated in this double-blind, placebo controlled, cross-over trial with either buspirone HCl 30 mg twice daily or placebo for 3 months. Buspirone was not shown to be superior to placebo in the treatment of patients with SCA.

KW - Ataxia

KW - Buspirone

KW - SCA

UR - https://www.scopus.com/pages/publications/34547683197

UR - https://www.scopus.com/pages/publications/34547683197#tab=citedBy

U2 - 10.1016/j.jns.2007.04.019

DO - 10.1016/j.jns.2007.04.019

M3 - Article

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AN - SCOPUS:34547683197

SN - 0022-510X

VL - 260

SP - 143

EP - 146

JO - Journal of the Neurological Sciences

JF - Journal of the Neurological Sciences

IS - 1-2

ER -

Treatment of spinocerebellar ataxia with buspirone

Abstract

Keywords

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