Abstract
Four patients with refractory cutaneous T-cell lymphoma (mycosis fungoides) were treated with 13-cis-retinoic acid. Near complete clearing of extensive tumours and plaques was seen in one patient, who remains in partial remission with continued improvement after fifteen months. Two patients showed improvement in pruritus and 50% reduction in plaques by four and six weeks, respectively. The fourth patient had improvement in pruritus and clearing of plaques, but dryness and scaling necessitated reduction and eventually withdrawal of the treatment.
Original language | English (US) |
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Pages (from-to) | 1345-1347 |
Number of pages | 3 |
Journal | The Lancet |
Volume | 321 |
Issue number | 8338 |
DOIs | |
State | Published - Jun 18 1983 |
Externally published | Yes |
Bibliographical note
Funding Information:This work was supported by grants from the NIH (CA 27502, CA 23074, CA 17094) and Hoffman-LaRoche, Inc.