Trapping interactions between catalytic domains and carrier proteins of modular biosynthetic enzymes with chemical probes

Keyphrases

• Natural Products 100%
• Chemical Probes 100%
• Carrier Protein 100%
• Catalytic Domain 100%
• Biosynthetic Enzymes 100%
• Polyketide Synthase 66%
• Nonribosomal Peptide Synthetase 66%
• Biophysical Studies 33%
• Chemical Tools 33%
• Multi-domain 33%
• Structural Mechanism 33%
• Immunosuppressive Activity 33%
• Anticancer Activity 33%
• Functional Investigation 33%
• Structural Investigation 33%
• Modular Enzyme 33%
• Transient Interactions 33%
• Biochemical Studies 33%
• Synthetic Intermediate 33%
• Antibacterial & Antifungal Activity 33%
• Peptidyl Carrier Protein 33%
• Acyl Carrier Protein 33%
• Modular Architecture 33%
• Novel Chemicals 33%

Biochemistry, Genetics and Molecular Biology

• Enzyme 100%
• Enzyme Active Site 100%
• Nonribosomal Peptide 50%
• Polyketide Synthase 50%
• Antibacterial Activity 25%
• Antineoplastic Activity 25%
• Acyl Carrier Protein 25%
• Antifungal Activity 25%