Transposons for cancer gene discovery: Sleeping beauty and beyond

Lara S. Collier, David A. Largaespada

Research output: Contribution to journalReview article

23 Scopus citations

Abstract

The use of Sleeping Beauty transposons as somatic mutagens to discover cancer genes in hematopoietic tumors and sarcomas has been documented. Here, we discuss the future of Sleeping Beauty for cancer genetic studies and the potential use of additional transposable elements for somatic mutagenesis.

Original languageEnglish (US)
Article numberS15
JournalGenome biology
Volume8
Issue numberSUPPL. 1
DOIs
StatePublished - Oct 31 2007

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