Transplantation studies reveal internuclear transfer of toxic RNA in engrafted muscles of myotonic dystrophy 1 mice

Keyphrases

• Alternative Splicing 66%
• Autosomal Dominant 33%
• Cell Transplantation 33%
• CUG Repeats 66%
• Donor-derived 66%
• Engraftment 66%
• Form Focus 33%
• Human Pluripotent Stem Cells (hPSCs) 33%
• Immunodeficiency 33%
• In Situ 33%
• MBNL1 33%
• Mexico 33%
• Model Combining 33%
• Mouse Model 66%
• Muscular Dystrophy 100%
• Myofiber 33%
• Myogenic Progenitors 33%
• Myonuclei 33%
• Myotonic Dystrophy 100%
• NIH Funding 33%
• Pathological Effect 33%
• Potential Therapeutics 33%
• RNA Foci 66%
• Sequestration 33%
• Skeletal muscle Atrophy 33%
• Splicing Pattern 33%
• Stem Cell Transplantation 33%
• Stem Cell-derived 33%
• Syncytial 33%
• Therapeutic Potential 33%
• Toxic RNA 100%
• Transplant Experiment 100%

Medicine and Dentistry

• Alternative RNA Splicing 66%
• Autosomal Dominant Inheritance 33%
• Cell Transplantation 33%
• Engraftment 66%
• Human Pluripotent Stem Cell 33%
• Immune Deficiency 33%
• Muscle Disease 33%
• Muscular Dystrophy 100%
• Myotonic Dystrophy 100%
• Skeletal Muscle 33%
• Stem Cell Therapy 33%

Biochemistry, Genetics and Molecular Biology

• Alternative Splicing 40%
• Autosomal Dominant Inheritance 20%
• Cell Transplantation 20%
• MBNL1 20%
• Mouse Model 40%
• RNA 100%
• Skeletal Muscle 20%
• Stem Cell 20%
• Stem Cell Transplantation 20%