Transmission of Salmonella typhimurium to swine

Paula J. Fedorka-Cray, Shannon C. Whipp, Richard E. Isaacson, Nels Nord, Kris Lager

Research output: Contribution to journalArticlepeer-review

80 Scopus citations

Abstract

These studies were designed to determine the rate of transmission and the colonization pattern of Salmonella typhimurium in swine. Two experiments were conducted. In experiment 1, swine challenged per os with either S. typhimurium strain 798T + or strain 798N + were exposed to heterologous feces. Following exposure to heterologous strains, heterologous Salmonella were recovered from the feces of infected swine within 3 days and from the tonsil and ileum at necropsy. Bacterial populations in swine initially challenged with Salmonella remained constant. In experiment 2, Salmonella-free swine were commingled with a population of pigs that were shedding 2.69 log10 CFU Salmonella/ gram feces. Salmonella was recovered from pooled fecal samples from the commingled swine on day 2 post-exposure to the infected group. Low numbers of Salmonella were detected in the ileocolic lymph node, ileum, cecum or spleen of all commingled swine throughout the necropsy period. These data provide a means for evaluating transmission of Salmonella to a population of swine which may be used to study the mechanisms involved in transmission and maintenance of the disease.

Original languageEnglish (US)
Pages (from-to)333-344
Number of pages12
JournalVeterinary Microbiology
Volume41
Issue number4
DOIs
StatePublished - Aug 15 1994

Keywords

  • Carrier
  • Pig
  • Salmonella typhimurium
  • Transmission
  • Zooneses

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