Translocation of ligand conformational free energy in receptor activation: A possible functional role of conformational isomerism in drug action

Research output: Contribution to journalArticlepeer-review

7 Scopus citations
Original languageEnglish (US)
Pages (from-to)806-807
Number of pages2
JournalJournal of Pharmaceutical Sciences
Issue number5
StatePublished - May 1971

Bibliographical note

Funding Information:
Received November 13, 1970. Minneapolis, MN 55455 Accepted for publication January 27, 1971. The author is indebted to Dr. Edward G. Rippie for helpful discussions. Supported in part by National Institutes of Health Grant GM- 09402.

Copyright 2018 Elsevier B.V., All rights reserved.


  • Conformation isomerism relationship—biological activity
  • Ligand conformational free energy—receptor activation

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