Translating pharmacogenomics discoveries into the clinic: An implementation framework

R. S. Huang; Eric R. Gamazon

doi:10.1186/gm497

Translating pharmacogenomics discoveries into the clinic: An implementation framework

R. S. Huang
, Eric R. Gamazon

Experimental and Clinical Pharmacology

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The implementation of pharmacogenomics-guided care has the potential to improve clinical outcomes; however, the adoption of pharmacogenomics into clinical practice remains slow. This is partly due to the lack of a standardized framework for translating key findings into diagnostic tests. A recent study describes a comprehensive system developed by the Coriell Personalized Medicine Collaborative for facilitating the translation of genomic findings into clinical practice, and its application for seven commonly prescribed drugs.

Original language	English (US)
Article number	94
Journal	Genome medicine
Volume	5
Issue number	10
DOIs	https://doi.org/10.1186/gm497
State	Published - Oct 18 2013

Bibliographical note

Funding Information:
RSH received support from NIH/NIGMS grant K08GM089941, a Circle of Service Foundation Early Career Investigator award, University of Chicago Cancer Center Support Grant (#P30 CA14599), Breast Cancer SPORE Career Development Award (CA125183), NIH/NCI grant R21 CA139278, NIH/NIGMS grant UO1GM61393, a Conquer Cancer Foundation of ASCO Translational Research Professorship award in memory of Merrill J Egorin, MD, and a pilot grant from NIH/NCATS grant UL1RR024999.

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abstract = "The implementation of pharmacogenomics-guided care has the potential to improve clinical outcomes; however, the adoption of pharmacogenomics into clinical practice remains slow. This is partly due to the lack of a standardized framework for translating key findings into diagnostic tests. A recent study describes a comprehensive system developed by the Coriell Personalized Medicine Collaborative for facilitating the translation of genomic findings into clinical practice, and its application for seven commonly prescribed drugs.",

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N2 - The implementation of pharmacogenomics-guided care has the potential to improve clinical outcomes; however, the adoption of pharmacogenomics into clinical practice remains slow. This is partly due to the lack of a standardized framework for translating key findings into diagnostic tests. A recent study describes a comprehensive system developed by the Coriell Personalized Medicine Collaborative for facilitating the translation of genomic findings into clinical practice, and its application for seven commonly prescribed drugs.

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Translating pharmacogenomics discoveries into the clinic: An implementation framework

Abstract

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