Translating pharmacogenomics discoveries into the clinic: An implementation framework

R. S. Huang, Eric R. Gamazon

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The implementation of pharmacogenomics-guided care has the potential to improve clinical outcomes; however, the adoption of pharmacogenomics into clinical practice remains slow. This is partly due to the lack of a standardized framework for translating key findings into diagnostic tests. A recent study describes a comprehensive system developed by the Coriell Personalized Medicine Collaborative for facilitating the translation of genomic findings into clinical practice, and its application for seven commonly prescribed drugs.

Original languageEnglish (US)
Article number94
JournalGenome medicine
Volume5
Issue number10
DOIs
StatePublished - Oct 18 2013

Bibliographical note

Funding Information:
RSH received support from NIH/NIGMS grant K08GM089941, a Circle of Service Foundation Early Career Investigator award, University of Chicago Cancer Center Support Grant (#P30 CA14599), Breast Cancer SPORE Career Development Award (CA125183), NIH/NCI grant R21 CA139278, NIH/NIGMS grant UO1GM61393, a Conquer Cancer Foundation of ASCO Translational Research Professorship award in memory of Merrill J Egorin, MD, and a pilot grant from NIH/NCATS grant UL1RR024999.

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