Transition-metal-mediated routes to 3,3-disubstituted oxindoles through anilide cyclisation

Johannes E.M.N. Klein; Richard J.K. Taylor

doi:10.1002/ejoc.201100836

Transition-metal-mediated routes to 3,3-disubstituted oxindoles through anilide cyclisation

Johannes E.M.N. Klein, Richard J.K. Taylor

Research output: Contribution to journal › Review article › peer-review

316 Scopus citations

Abstract

This review describes transition-metal-catalysed and -mediated processes for the preparation of oxindoles from anilides through C(3)-C(3a) bond formation. Traditional methods, such as the Heck reaction, and recent developments, including direct Ar-H coupling processes, are presented, as are applications in natural product synthesis.

Original language	English (US)
Pages (from-to)	6821-6841
Number of pages	21
Journal	European Journal of Organic Chemistry
Issue number	34
DOIs	https://doi.org/10.1002/ejoc.201100836
State	Published - Dec 2011
Externally published	Yes

Keywords

C-H activation
Enolate arylations
Heck reaction
Natural product synthesis
Oxindoles
Synthesis
Transition metals

Publisher link

10.1002/ejoc.201100836

Find It

Find It at U of M Libraries

Cite this

@article{8b68b7200fa641d7b50ecf765f890f55,

title = "Transition-metal-mediated routes to 3,3-disubstituted oxindoles through anilide cyclisation",

abstract = "This review describes transition-metal-catalysed and -mediated processes for the preparation of oxindoles from anilides through C(3)-C(3a) bond formation. Traditional methods, such as the Heck reaction, and recent developments, including direct Ar-H coupling processes, are presented, as are applications in natural product synthesis.",

keywords = "C-H activation, Enolate arylations, Heck reaction, Natural product synthesis, Oxindoles, Synthesis, Transition metals",

author = "Klein, \{Johannes E.M.N.\} and Taylor, \{Richard J.K.\}",

year = "2011",

month = dec,

doi = "10.1002/ejoc.201100836",

language = "English (US)",

pages = "6821--6841",

journal = "European Journal of Organic Chemistry",

issn = "1434-193X",

publisher = "Wiley-VCH Verlag",

number = "34",

}

TY - JOUR

T1 - Transition-metal-mediated routes to 3,3-disubstituted oxindoles through anilide cyclisation

AU - Klein, Johannes E.M.N.

AU - Taylor, Richard J.K.

PY - 2011/12

Y1 - 2011/12

N2 - This review describes transition-metal-catalysed and -mediated processes for the preparation of oxindoles from anilides through C(3)-C(3a) bond formation. Traditional methods, such as the Heck reaction, and recent developments, including direct Ar-H coupling processes, are presented, as are applications in natural product synthesis.

AB - This review describes transition-metal-catalysed and -mediated processes for the preparation of oxindoles from anilides through C(3)-C(3a) bond formation. Traditional methods, such as the Heck reaction, and recent developments, including direct Ar-H coupling processes, are presented, as are applications in natural product synthesis.

KW - C-H activation

KW - Enolate arylations

KW - Heck reaction

KW - Natural product synthesis

KW - Oxindoles

KW - Synthesis

KW - Transition metals

UR - https://www.scopus.com/pages/publications/81855210999

UR - https://www.scopus.com/inward/citedby.url?scp=81855210999&partnerID=8YFLogxK

U2 - 10.1002/ejoc.201100836

DO - 10.1002/ejoc.201100836

M3 - Review article

AN - SCOPUS:81855210999

SN - 1434-193X

SP - 6821

EP - 6841

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

IS - 34

ER -

Transition-metal-mediated routes to 3,3-disubstituted oxindoles through anilide cyclisation

Abstract

Keywords

Publisher link

Find It

Other files and links

Fingerprint

Cite this