Transfusion Algorithms and How They Apply to Blood Conservation: The High-risk Cardiac Surgical Patient

Marie E. Steiner, George John Despotis

Research output: Contribution to journalReview articlepeer-review

35 Scopus citations

Abstract

Considerable blood product support is administered to the cardiac surgery population. Due to the multifactorial etiology of bleeding in the cardiac bypass patient, blood products frequently and empirically are infused to correct bleeding, with varying success. Several studies have demonstrated the benefit of algorithm-guided transfusion in reducing blood loss, transfusion exposure, or rate of surgical re-exploration for bleeding. Some transfusion algorithms also incorporate laboratory-based decision points in their guidelines. Despite published success with standardized transfusion practices, generalized change in blood use has not been realized, and it is evident that current laboratory-guided hemostasis measures are inadequate to define and address the bleeding etiology in these patients.

Original languageEnglish (US)
Pages (from-to)177-184
Number of pages8
JournalHematology/Oncology Clinics of North America
Volume21
Issue number1
DOIs
StatePublished - Feb 2007

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