Transcranial Direct Current Stimulation: Mechanisms and Psychiatric Applications

Daniel L. Kenney-Jung, Caren J. Blacker, Deniz Doruk Camsari, Jonathan C. Lee, Charles P. Lewis

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Transcranial direct current stimulation (tDCS) involves the application of weak electric current to the scalp. tDCS may influence brain functioning through effects on cortical excitability, neural plasticity, and learning. Evidence in adults suggests promising therapeutic applications for depression, and the adverse effect profile is generally mild. Early research indicates complex interactions between tDCS and concurrent cognitive and motor tasks. Further investigation is warranted to understand how tDCS impacts processes relevant to psychiatric conditions.

Original languageEnglish (US)
Pages (from-to)53-60
Number of pages8
JournalChild and adolescent psychiatric clinics of North America
Issue number1
StatePublished - Jan 2019

Bibliographical note

Funding Information:
Disclosures: C.J. Blacker, D. Doruk Camsari, and C.P. Lewis receive research support from the Mayo Clinic Foundation Departmental Small Grant Program. C.P. Lewis is a site investigator for multicenter studies funded by Neuronetics, Inc and NeoSync, Inc. D.L. Kenney-Jung and J.C. Lee have no financial disclosures.

Publisher Copyright:
© 2018 Elsevier Inc.


  • Applications
  • Mechanisms
  • Neuromodulation
  • Noninvasive brain stimulation
  • Transcranial direct current stimulation


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