TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO

Keyphrases

• Induced Apoptosis 100%
• Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) 100%
• DIABLO 100%
• Smac 100%
• Mitochondria 42%
• Mitochondrium 42%
• Cancer Cells 28%
• Cell Death 28%
• Apoptosis 28%
• Death Receptor 14%
• Apoptotic Pathway 14%
• Cytochrome c (Cyt c) 14%
• Receptor-mediated Apoptosis 14%
• Mitochondrial Pathway 14%
• Inhibitory Effect 14%
• Caspase-3 Activation 14%
• Caspase-8 14%
• Caspase-3 14%
• Active Form 14%
• Death Ligands 14%
• Caspase-9 Activity 14%
• Cell Death Receptors 14%
• TBid 14%
• Caspase-8 Activation 14%
• 3′-processing 14%

Neuroscience

• Tumor Necrosis Factor Related Apoptosis Inducing Ligand 100%
• Programmed Cell Death 100%
• Mitochondrion 42%
• Cell Death 42%
• Caspase 3 28%
• XIAP 28%
• Caspase 8 28%
• Death Receptor 28%
• Caspase-9 14%
• Cytochrome C 14%

Biochemistry, Genetics and Molecular Biology

• Tumor Necrosis Factor 100%
• Programmed Cell Death 100%
• Mitochondrion 23%
• Cell Death 23%
• XIAP 15%
• Cancer Cell 15%
• Caspase 8 15%
• Caspase 3 15%
• Caspase-9 7%
• Cytochrome C 7%
• Deficiency 7%