Traditional and emerging antifungal therapies

Tamra M. Arnold, Emily Dotson, George A. Sarosi, Chadi A. Hage

Research output: Contribution to journalReview articlepeer-review

38 Scopus citations


Invasive mycoses continue to be a major problem in the growing population of immunosuppressed patients. More antifungal agents are now available than ever. The options are many, with more efficacies and less toxicity than in the past. These agents differ in terms of spectrum of activity, pharmacologic properties, and indications. In this article we discuss the three major classes of antifungal agents: the polyens, the triazoles, and the echinocandins. The emphasis is placed on their clinical use, side effects, drug interactions, and other practical issues.

Original languageEnglish (US)
Pages (from-to)222-228
Number of pages7
JournalProceedings of the American Thoracic Society
Issue number3
StatePublished - May 15 2010


  • Azoles
  • Echinocandins
  • Invasive fungal infection
  • Polyenes


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