Towards advanced chemical and biological nanosensors - An overview

Chanda Ranjit Yonzon; Douglas A. Stuart; Xiaoyu Zhang; Adam D. McFarland; Christy L. Haynes; Richard P. Van Duyne

doi:10.1016/j.talanta.2005.06.039

Towards advanced chemical and biological nanosensors - An overview

Chanda Ranjit Yonzon, Douglas A. Stuart, Xiaoyu Zhang, Adam D. McFarland, Christy L. Haynes, Richard P. Van Duyne

Chemistry (Twin Cities)

Research output: Contribution to journal › Article › peer-review

351 Scopus citations

Abstract

This paper reviews recent developments in the design and application of two types of optical nanosensor, those based on: (1) localized surface plasmon resonance (LSPR) spectroscopy and (2) surface-enhanced Raman scattering (SERS). The performance of these sensors is discussed in the context of biological and chemical sensing. The first section addresses the LSPR sensors. Arrays of nanotriangles were evaluated and characterized using realistic protein/ligand interactions. Isolated, single nanoparticles were used for chemosensing and performed comparably to the nanoparticle array sensors. In particular, we highlight the effect of nanoparticle morphology on sensing response. The second section details the use of SERS sensors using metal film over nanosphere (MFON) surfaces. The high SERS enhancements and long-term stability of MFONs were exploited in order to develop SERS-based sensors for two important target molecules: a Bacillus anthracis biomarker and glucose in a serum protein mixture.

Original language	English (US)
Pages (from-to)	438-448
Number of pages	11
Journal	Talanta
Volume	67
Issue number	3
DOIs	https://doi.org/10.1016/j.talanta.2005.06.039
State	Published - Sep 15 2005

Bibliographical note

Funding Information:
This work was supported by the National Science Foundation (EEC-0118025, DMR-0076097, CHE-0414554), the Air Force Office of Scientific Research MURI program (F49620-02-1-0381), and the National Institutes of Health (1 R21 DK066990-01A1).

Keywords

Localized surface plasmon resonance
Metal film over nanosphere
Nanosensor
Nanosphere lithography
Surface-enhanced Raman scattering

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10.1016/j.talanta.2005.06.039

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abstract = "This paper reviews recent developments in the design and application of two types of optical nanosensor, those based on: (1) localized surface plasmon resonance (LSPR) spectroscopy and (2) surface-enhanced Raman scattering (SERS). The performance of these sensors is discussed in the context of biological and chemical sensing. The first section addresses the LSPR sensors. Arrays of nanotriangles were evaluated and characterized using realistic protein/ligand interactions. Isolated, single nanoparticles were used for chemosensing and performed comparably to the nanoparticle array sensors. In particular, we highlight the effect of nanoparticle morphology on sensing response. The second section details the use of SERS sensors using metal film over nanosphere (MFON) surfaces. The high SERS enhancements and long-term stability of MFONs were exploited in order to develop SERS-based sensors for two important target molecules: a Bacillus anthracis biomarker and glucose in a serum protein mixture.",

keywords = "Localized surface plasmon resonance, Metal film over nanosphere, Nanosensor, Nanosphere lithography, Surface-enhanced Raman scattering",

author = "Yonzon, {Chanda Ranjit} and Stuart, {Douglas A.} and Xiaoyu Zhang and McFarland, {Adam D.} and Haynes, {Christy L.} and {Van Duyne}, {Richard P.}",

note = "Funding Information: This work was supported by the National Science Foundation (EEC-0118025, DMR-0076097, CHE-0414554), the Air Force Office of Scientific Research MURI program (F49620-02-1-0381), and the National Institutes of Health (1 R21 DK066990-01A1). ",

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AU - McFarland, Adam D.

AU - Haynes, Christy L.

AU - Van Duyne, Richard P.

N1 - Funding Information: This work was supported by the National Science Foundation (EEC-0118025, DMR-0076097, CHE-0414554), the Air Force Office of Scientific Research MURI program (F49620-02-1-0381), and the National Institutes of Health (1 R21 DK066990-01A1).

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N2 - This paper reviews recent developments in the design and application of two types of optical nanosensor, those based on: (1) localized surface plasmon resonance (LSPR) spectroscopy and (2) surface-enhanced Raman scattering (SERS). The performance of these sensors is discussed in the context of biological and chemical sensing. The first section addresses the LSPR sensors. Arrays of nanotriangles were evaluated and characterized using realistic protein/ligand interactions. Isolated, single nanoparticles were used for chemosensing and performed comparably to the nanoparticle array sensors. In particular, we highlight the effect of nanoparticle morphology on sensing response. The second section details the use of SERS sensors using metal film over nanosphere (MFON) surfaces. The high SERS enhancements and long-term stability of MFONs were exploited in order to develop SERS-based sensors for two important target molecules: a Bacillus anthracis biomarker and glucose in a serum protein mixture.

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KW - Nanosphere lithography

KW - Surface-enhanced Raman scattering

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Towards advanced chemical and biological nanosensors - An overview

Abstract

Bibliographical note

Keywords

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