Toward personalized therapy in AML: In vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML

K. M. Bernot; R. F. Siebenaler; S. P. Whitman; N. A. Zorko; G. G. Marcucci; R. Santhanam; E. H. Ahmed; M. Ngangana; K. K. McConnell; J. S. Nemer; D. L. Brook; S. K. Kulp; C. S. Chen; D. Frankhouser; P. Yan; R. Bundschuh; X. Zhang; A. M. Dorrance; K. E. Dickerson; D. Jarjoura; W. Blum; G. Marcucci; M. A. Caligiuri

doi:10.1038/leu.2013.147

Toward personalized therapy in AML: In vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML

K. M. Bernot, R. F. Siebenaler, S. P. Whitman, N. A. Zorko, G. G. Marcucci, R. Santhanam, E. H. Ahmed, M. Ngangana, K. K. McConnell, J. S. Nemer, D. L. Brook, S. K. Kulp, C. S. Chen, D. Frankhouser, P. Yan, R. Bundschuh, X. Zhang, A. M. Dorrance, K. E. Dickerson, D. JarjouraW. Blum, G. Marcucci, M. A. Caligiuri

Research output: Contribution to journal › Letter › peer-review

13 Scopus citations

Original language	English (US)
Pages (from-to)	2379-2382
Number of pages	4
Journal	Leukemia
Volume	27
Issue number	12
DOIs	https://doi.org/10.1038/leu.2013.147
State	Published - Dec 2013
Externally published	Yes

Bibliographical note

Funding Information:
We thank The Ohio State University Comprehensive Cancer Center’s Shared Resources: Biostatistics, Nucleic Acid, Comparative Pathology and Mouse Phenotyping and Analytical Cytometry. This work was supported in part by National Cancer Institute, Bethesda, MD, USA, grants: to MAC (CA089341; CA009338), to GM (CA102031), to MAC and GM (CA140158), to NAZ (T32 GM12453), and to KMB (T32 CA009338). We also thank the Thomas J. Bardos Science Education Award (RFS), the American Society of Hematology Trainee Research Award (RFS), the OSU College of Medicine Fellowship (NAZ), Pelotonia Fellowships (NAZ, RFS, and AMD), Wells Family Fellowship (JSN and DLB) and the American Society of Hematology Minority Medical Student Award Program (MN).

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Bernot, K. M., Siebenaler, R. F., Whitman, S. P., Zorko, N. A., Marcucci, G. G., Santhanam, R., Ahmed, E. H., Ngangana, M., McConnell, K. K., Nemer, J. S., Brook, D. L., Kulp, S. K., Chen, C. S., Frankhouser, D., Yan, P., Bundschuh, R., Zhang, X., Dorrance, A. M., Dickerson, K. E., ... Caligiuri, M. A. (2013). Toward personalized therapy in AML: In vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML. Leukemia, 27(12), 2379-2382. https://doi.org/10.1038/leu.2013.147

Bernot, KM, Siebenaler, RF, Whitman, SP, Zorko, NA, Marcucci, GG, Santhanam, R, Ahmed, EH, Ngangana, M, McConnell, KK, Nemer, JS, Brook, DL, Kulp, SK, Chen, CS, Frankhouser, D, Yan, P, Bundschuh, R, Zhang, X, Dorrance, AM, Dickerson, KE, Jarjoura, D, Blum, W, Marcucci, G & Caligiuri, MA 2013, 'Toward personalized therapy in AML: In vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML', Leukemia, vol. 27, no. 12, pp. 2379-2382. https://doi.org/10.1038/leu.2013.147

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title = "Toward personalized therapy in AML: In vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML",

author = "Bernot, {K. M.} and Siebenaler, {R. F.} and Whitman, {S. P.} and Zorko, {N. A.} and Marcucci, {G. G.} and R. Santhanam and Ahmed, {E. H.} and M. Ngangana and McConnell, {K. K.} and Nemer, {J. S.} and Brook, {D. L.} and Kulp, {S. K.} and Chen, {C. S.} and D. Frankhouser and P. Yan and R. Bundschuh and X. Zhang and Dorrance, {A. M.} and Dickerson, {K. E.} and D. Jarjoura and W. Blum and G. Marcucci and Caligiuri, {M. A.}",

note = "Funding Information: We thank The Ohio State University Comprehensive Cancer Center{\textquoteright}s Shared Resources: Biostatistics, Nucleic Acid, Comparative Pathology and Mouse Phenotyping and Analytical Cytometry. This work was supported in part by National Cancer Institute, Bethesda, MD, USA, grants: to MAC (CA089341; CA009338), to GM (CA102031), to MAC and GM (CA140158), to NAZ (T32 GM12453), and to KMB (T32 CA009338). We also thank the Thomas J. Bardos Science Education Award (RFS), the American Society of Hematology Trainee Research Award (RFS), the OSU College of Medicine Fellowship (NAZ), Pelotonia Fellowships (NAZ, RFS, and AMD), Wells Family Fellowship (JSN and DLB) and the American Society of Hematology Minority Medical Student Award Program (MN).",

year = "2013",

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doi = "10.1038/leu.2013.147",

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T2 - In vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML

AU - Bernot, K. M.

AU - Siebenaler, R. F.

AU - Whitman, S. P.

AU - Zorko, N. A.

AU - Marcucci, G. G.

AU - Santhanam, R.

AU - Ahmed, E. H.

AU - Ngangana, M.

AU - McConnell, K. K.

AU - Nemer, J. S.

AU - Brook, D. L.

AU - Kulp, S. K.

AU - Chen, C. S.

AU - Frankhouser, D.

AU - Yan, P.

AU - Bundschuh, R.

AU - Zhang, X.

AU - Dorrance, A. M.

AU - Dickerson, K. E.

AU - Jarjoura, D.

AU - Blum, W.

AU - Marcucci, G.

AU - Caligiuri, M. A.

N1 - Funding Information: We thank The Ohio State University Comprehensive Cancer Center’s Shared Resources: Biostatistics, Nucleic Acid, Comparative Pathology and Mouse Phenotyping and Analytical Cytometry. This work was supported in part by National Cancer Institute, Bethesda, MD, USA, grants: to MAC (CA089341; CA009338), to GM (CA102031), to MAC and GM (CA140158), to NAZ (T32 GM12453), and to KMB (T32 CA009338). We also thank the Thomas J. Bardos Science Education Award (RFS), the American Society of Hematology Trainee Research Award (RFS), the OSU College of Medicine Fellowship (NAZ), Pelotonia Fellowships (NAZ, RFS, and AMD), Wells Family Fellowship (JSN and DLB) and the American Society of Hematology Minority Medical Student Award Program (MN).

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Toward personalized therapy in AML: In vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML

Bibliographical note

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