Toward network biology in E. Coli cell

Hirotada Mori, Rikiya Takeuchi, Yuta Otsuka, Steven Bowden, Katsushi Yokoyama, Ai Muto, Igor Libourel, Barry L. Wanner

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations


E. coli has been a critically important model research organism for more than 50 years, particularly in molecular biology. In 1997, the E. coli draft genome sequence was published. Post-genomic techniques and resources were then developed that allowed E. coli to become a model organism for systems biology. Progress made since publication of the E. coli genome sequence will be summarized.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Number of pages14
StatePublished - 2015

Publication series

NameAdvances in Experimental Medicine and Biology
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Bibliographical note

Funding Information:
I thank to Dr. Gen-ichi Sampei for kindly giving us the F plasmid. This work was supported by the Create Revolutionary Technological Seeds for Science and Technology (CREST) from JST (Japan Science and Technology Agency), Grant-in-Aid for Scientific Research (A), Innovation Areas “Biosynthetic machinery” from the Ministry of Education, Culture, Sports, Science and Technology of Japan, and the Exploratory Research for Advanced Technology (ERATO).

Publisher Copyright:
© Springer International Publishing Switzerland 2015.


  • E. coli
  • Network biology
  • Plasmid clone libraries


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