Total Synthesis of dl-Ancistrofuran: A Study of Cyclic Ether Formation

Keyphrases

• Cyclization 100%
• Total Synthesis 100%
• Cyclic Ethers 100%
• Ether Formation 100%
• Lactones 66%
• Anions 33%
• Dienes 33%
• Tetrahydrofuran 33%
• Chloride 33%
• Epimer 33%
• Phenylthio 33%
• Enolates 33%
• Zinc Chloride 33%
• Aldol Condensation 33%
• Alkylidene 33%
• γ-butyrolactone 33%
• Mercuric Ion 33%
• Six-step 33%

Chemistry

• Lactone 100%
• Cyclic Ether 100%
• formation 100%
• Tetrahydrofuran 50%
• Epimer 50%
• Enolates 50%
• Aldol Condensation 50%
• Zinc Chloride 50%