This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the benefits and harms of total knee arthroplasty (TKA) compared to conservative treatment including continued medical therapy, other therapies such as physical therapy, acupuncture etc. or no treatment in patients with knee osteoarthritis and other non-traumatic diseases with refractory symptoms.
Bibliographical noteFunding Information:
JAS: JAS has received research grants from Takeda, and Savient, and consultant fees from Regeneron, Allergan, Takeda and Savient; he is a member of the executive of OMERACT, an organization that develops outcome measures in rheumatology and receives arms-length funding from 36 companies.
© 2013 The Cochrane Collaboration.