TY - JOUR
T1 - Total Joint Arthroplasty in Patients with Chronic Renal Disease
T2 - Is It Worth the Risk?
AU - Warth, Lucian C.
AU - Pugely, Andrew J.
AU - Martin, Christopher T.
AU - Gao, Yubo
AU - Callaghan, John J.
N1 - Publisher Copyright:
© 2015 Elsevier Inc..
Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - 26-27% of patients with end stage hip and knee arthritis requiring TJR have chronic renal disease. A multi-center, prospective clinical registry was queried for TJA's from 2006 to 2012, and 74,300 cases were analyzed. Renal impairment was quantified using estimated glomerular filtration rate (eGFR) to stratify each patient by stage of CRD (1-5). There was a significantly greater rate of overall complications in patients with moderate to severe CRD (6.1% vs. 7.6%, P < 0.001). In those with CRD (Stage 3-5), mortality was twice as high (0.26% vs. 0.48%, P < 0.001). Patients with Stage 4 and 5 CRD had a 213% increased risk of any complication (OR 2.13, 95% CI: 1.73-2.62). Surgeons may use these findings to discuss the risk-benefit ratio of elective TJR in patients with CRD.
AB - 26-27% of patients with end stage hip and knee arthritis requiring TJR have chronic renal disease. A multi-center, prospective clinical registry was queried for TJA's from 2006 to 2012, and 74,300 cases were analyzed. Renal impairment was quantified using estimated glomerular filtration rate (eGFR) to stratify each patient by stage of CRD (1-5). There was a significantly greater rate of overall complications in patients with moderate to severe CRD (6.1% vs. 7.6%, P < 0.001). In those with CRD (Stage 3-5), mortality was twice as high (0.26% vs. 0.48%, P < 0.001). Patients with Stage 4 and 5 CRD had a 213% increased risk of any complication (OR 2.13, 95% CI: 1.73-2.62). Surgeons may use these findings to discuss the risk-benefit ratio of elective TJR in patients with CRD.
KW - ACS NSQIP
KW - Chronic renal disease
KW - Database
KW - EGFR (estimated glomerular filtration rate)
KW - Total joint arthroplasty
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U2 - 10.1016/j.arth.2014.12.037
DO - 10.1016/j.arth.2014.12.037
M3 - Article
C2 - 26122111
AN - SCOPUS:84940895015
SN - 0883-5403
VL - 30
SP - 51
EP - 54
JO - Journal of Arthroplasty
JF - Journal of Arthroplasty
IS - 9
ER -