Topological stress is responsible for the detrimental outcomes of head-on replication-transcription conflicts

Keyphrases

• Supercoil 100%
• Transcription-replication Conflicts 100%
• Gram-positive 50%
• Topoisomerase II 50%
• Genome Organization 50%
• Conflict Resolution 50%
• Replication Machinery 50%
• Genome Evolution 50%
• Gyrase 50%
• DNA Gyrase 50%
• Transcription Machinery 50%
• Bacillus Subtilis (B. subtilis) 50%
• Chromosome Duplication 50%
• Topo IV 50%
• Lagging Strand 50%
• Leading Strand 50%
• Negative Supercoiling 50%
• Across Species 50%
• Conflict Region 50%
• R-loop Formation 50%

Biochemistry, Genetics and Molecular Biology

• Transcription 100%
• Genome Organization 33%
• Gyrase 33%
• Type II Topoisomerase 33%
• R-Loop 33%
• DNA Gyrase 33%