Abstract
A total of 27 children with esotropia (mean age, 3.9 years; range, 9 months to 13.8 years) were enrolled in a 9-month observational study following botulinum toxin A (BTX-A) injection of one (n = 7) or both (n = 20) medial rectus muscles. BTX-A dosage ranged from 3.0 to 6.0 units per muscle. Three participants developed tonic pupil, noted at the first follow-up visit, occurring 12-19 days after injection. All 3 cases occurred in the left eye of participants who underwent bilateral BTX-A injection by the same surgeon. Anisocoria diminished from a maximum of 4 mm at the 2-week visit to 1-2 mm in all patients over the 9-month postinjection data collection period. No adverse visual outcomes were noted. Tonic pupil is an infrequently reported complication of BTX-A injection for strabismus. The experience of our investigator group suggests the need for careful injection technique and thorough preinjection counseling.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 78-81 |
| Number of pages | 4 |
| Journal | Journal of AAPOS |
| Volume | 20 |
| Issue number | 1 |
| DOIs | |
| State | Published - Feb 1 2016 |
Bibliographical note
Publisher Copyright:© 2016 American Association for Pediatric Ophthalmology and Strabismus.