Tobacco carcinogen research to aid understanding of cancer risk and influence policy

Hitesh Singhavi; Jasjit S. Ahluwalia; Irina Stepanov; Prakash C. Gupta; Vikram Gota; Pankaj Chaturvedi; Samir S. Khariwala

doi:10.1002/lio2.204

Tobacco carcinogen research to aid understanding of cancer risk and influence policy

Hitesh Singhavi, Jasjit S. Ahluwalia, Irina Stepanov, Prakash C. Gupta, Vikram Gota, Pankaj Chaturvedi, Samir S. Khariwala

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Education regarding the health effects associated with tobacco use has made important progress worldwide over the last few decades. Still, tobacco remains a significant cause of cancer and other diseases. As a result, significant worldwide morbidity and mortality is still attributable to tobacco use in modern times. Research into tobacco products, the carcinogens they contain, and how users metabolize them is an important benefit to the advancement of research aimed at reducing harm associated with tobacco use. This review summarizes the use of this type of research to study tobacco users’ risk of developing cancer, especially head and neck cancer. In addition, we discuss the use of tobacco research to provide support for increasing levels of federal regulation of tobacco products. Level of Evidence: 4.

Original language	English (US)
Pages (from-to)	372-376
Number of pages	5
Journal	Laryngoscope investigative otolaryngology
Volume	3
Issue number	5
DOIs	https://doi.org/10.1002/lio2.204
State	Published - Oct 2018

Bibliographical note

Publisher Copyright:
© 2018 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society.

Keywords

carcinogen
DNA adduct
Head and neck cancer
Level of Evidence
nitrosamines
tobacco

PubMed: MeSH publication types

Journal Article
Review

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Publisher link

10.1002/lio2.204

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209619/pdf/LIO2-3-372.pdf

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title = "Tobacco carcinogen research to aid understanding of cancer risk and influence policy",

abstract = "Education regarding the health effects associated with tobacco use has made important progress worldwide over the last few decades. Still, tobacco remains a significant cause of cancer and other diseases. As a result, significant worldwide morbidity and mortality is still attributable to tobacco use in modern times. Research into tobacco products, the carcinogens they contain, and how users metabolize them is an important benefit to the advancement of research aimed at reducing harm associated with tobacco use. This review summarizes the use of this type of research to study tobacco users{\textquoteright} risk of developing cancer, especially head and neck cancer. In addition, we discuss the use of tobacco research to provide support for increasing levels of federal regulation of tobacco products. Level of Evidence: 4.",

keywords = "carcinogen, DNA adduct, Head and neck cancer, Level of Evidence, nitrosamines, tobacco",

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note = "Publisher Copyright: {\textcopyright} 2018 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society.",

year = "2018",

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doi = "10.1002/lio2.204",

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AU - Singhavi, Hitesh

AU - Ahluwalia, Jasjit S.

AU - Stepanov, Irina

AU - Gupta, Prakash C.

AU - Gota, Vikram

AU - Chaturvedi, Pankaj

AU - Khariwala, Samir S.

PY - 2018/10

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N2 - Education regarding the health effects associated with tobacco use has made important progress worldwide over the last few decades. Still, tobacco remains a significant cause of cancer and other diseases. As a result, significant worldwide morbidity and mortality is still attributable to tobacco use in modern times. Research into tobacco products, the carcinogens they contain, and how users metabolize them is an important benefit to the advancement of research aimed at reducing harm associated with tobacco use. This review summarizes the use of this type of research to study tobacco users’ risk of developing cancer, especially head and neck cancer. In addition, we discuss the use of tobacco research to provide support for increasing levels of federal regulation of tobacco products. Level of Evidence: 4.

AB - Education regarding the health effects associated with tobacco use has made important progress worldwide over the last few decades. Still, tobacco remains a significant cause of cancer and other diseases. As a result, significant worldwide morbidity and mortality is still attributable to tobacco use in modern times. Research into tobacco products, the carcinogens they contain, and how users metabolize them is an important benefit to the advancement of research aimed at reducing harm associated with tobacco use. This review summarizes the use of this type of research to study tobacco users’ risk of developing cancer, especially head and neck cancer. In addition, we discuss the use of tobacco research to provide support for increasing levels of federal regulation of tobacco products. Level of Evidence: 4.

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KW - DNA adduct

KW - Head and neck cancer

KW - Level of Evidence

KW - nitrosamines

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Tobacco carcinogen research to aid understanding of cancer risk and influence policy

Abstract

Bibliographical note

Keywords

PubMed: MeSH publication types

UN SDGs

Publisher link

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