Tissue-engineered cultured periosteum sheet application to treat infrabony defects: Case series and 5-year results

Kazuhiro Okuda; Tomoyuki Kawase; Masaki Nagata; Kanoko Yamamiya; Koh Nakata; Larry F. Wolff; Hiromasa Yoshie

doi:10.11607/prd.1545

Tissue-engineered cultured periosteum sheet application to treat infrabony defects: Case series and 5-year results

Kazuhiro Okuda, Tomoyuki Kawase, Masaki Nagata, Kanoko Yamamiya, Koh Nakata, Larry F. Wolff, Hiromasa Yoshie

Periodontology

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

One-year data after autologous grafting of infrabony periodontal defects with human cultured periosteum sheets in combination with platelet-rich plasma and hydroxyapatite granules have shown favorable clinical and radiographic results. A 5-year follow-up evaluation of 22 selected patients indicated that treated infrabony defects remained stable. Radiographically, there was an increase in osseous radiopacity and bone trabeculation suggesting further bone maturation. This novel tissue-engineered periodontal treatment approach has resulted in significant clinical improvement, and defects remained stable after 5 years.

Original language	English (US)
Pages (from-to)	281-287
Number of pages	7
Journal	International Journal of Periodontics and Restorative Dentistry
Volume	33
Issue number	3
DOIs	https://doi.org/10.11607/prd.1545
State	Published - 2013

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title = "Tissue-engineered cultured periosteum sheet application to treat infrabony defects: Case series and 5-year results",

abstract = "One-year data after autologous grafting of infrabony periodontal defects with human cultured periosteum sheets in combination with platelet-rich plasma and hydroxyapatite granules have shown favorable clinical and radiographic results. A 5-year follow-up evaluation of 22 selected patients indicated that treated infrabony defects remained stable. Radiographically, there was an increase in osseous radiopacity and bone trabeculation suggesting further bone maturation. This novel tissue-engineered periodontal treatment approach has resulted in significant clinical improvement, and defects remained stable after 5 years.",

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AU - Okuda, Kazuhiro

AU - Kawase, Tomoyuki

AU - Nagata, Masaki

AU - Yamamiya, Kanoko

AU - Nakata, Koh

AU - Wolff, Larry F.

AU - Yoshie, Hiromasa

PY - 2013

Y1 - 2013

N2 - One-year data after autologous grafting of infrabony periodontal defects with human cultured periosteum sheets in combination with platelet-rich plasma and hydroxyapatite granules have shown favorable clinical and radiographic results. A 5-year follow-up evaluation of 22 selected patients indicated that treated infrabony defects remained stable. Radiographically, there was an increase in osseous radiopacity and bone trabeculation suggesting further bone maturation. This novel tissue-engineered periodontal treatment approach has resulted in significant clinical improvement, and defects remained stable after 5 years.

AB - One-year data after autologous grafting of infrabony periodontal defects with human cultured periosteum sheets in combination with platelet-rich plasma and hydroxyapatite granules have shown favorable clinical and radiographic results. A 5-year follow-up evaluation of 22 selected patients indicated that treated infrabony defects remained stable. Radiographically, there was an increase in osseous radiopacity and bone trabeculation suggesting further bone maturation. This novel tissue-engineered periodontal treatment approach has resulted in significant clinical improvement, and defects remained stable after 5 years.

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Tissue-engineered cultured periosteum sheet application to treat infrabony defects: Case series and 5-year results

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