Tin(II) compounds as catalysts for the Kabachnik-fields reaction under solvent-free conditions: Facile synthesis of α -aminophosphonates

Ricardo Gallardo-Macias, Kensaku Nakayama

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

In the presence of a catalytic amount of tin(II) salts, the three-component Kabachnik-Fields reaction involving aldehydes, amines, and diethyl phosphite proceeded smoothly to afford the corresponding -aminophosphonates in good to high yields. These reactions were carried out under solvent-free conditions.

Original languageEnglish (US)
Pages (from-to)57-62
Number of pages6
JournalSynthesis
Issue number1
DOIs
StatePublished - Feb 8 2010
Externally publishedYes

Keywords

  • α-aminophosphonates
  • Catalysis
  • Imines
  • Lewis acids
  • Solvent-free

Fingerprint

Dive into the research topics of 'Tin(II) compounds as catalysts for the Kabachnik-fields reaction under solvent-free conditions: Facile synthesis of α -aminophosphonates'. Together they form a unique fingerprint.

Cite this