Time-restricted eating improves quality of life measures in overweight humans

Ainslee Crose, Alison Alvear, Stephanie Singroy, Qi Wang, Emily Manoogian, Satchidananda Panda, Douglas G. Mashek, Lisa S. Chow

Research output: Contribution to journalArticlepeer-review

Abstract

Time-restricted eating (TRE) reduces weight in humans, but its effects on quality of life have not been well characterized. By performing a secondary analysis of a randomized clinical trial, we examined the effects of TRE (12-week intervention, 8 h eating window) vs. non-TRE (unrestricted eating) on quality of life (QoL) measures. Twenty subjects with overweight and prolonged eating window (mean (SD): 15.4 h (0.9)) were randomized to either 12 weeks of TRE (8 h eating window: (n = 11)) or non-TRE (n = 9). QoL data were collected with the 36-item Short Form Survey (SF-36) pre-and post-intervention. Given a two-way ANOVA model and post-hoc t-test analysis, the TRE group improved limitations due to emotional health (post-intervention: (+97.0 (10.0)) vs. baseline: (+66.7 (42.2) (p = 0.02) and perceived change in health over the last year (end intervention: (+68.2 (16.2) vs. baseline: (+52.3 (23.6) (p = 0.001) relative to baseline. The TRE group improved limitations due to emotional health (TRE: (+97.0 (10.0) vs. non-TRE: (+55.6 (44.1) (p = 0.05) and perceived change in health (TRE: (+68.2 (16.2) vs. non-TRE: (+44.4 (31.6) (p = 0.04) relative to the non-TRE group at post-intervention (p > 0.025). In conclusion, 12 weeks of TRE does not adversely affect QoL and may be associated with modest improvements in QoL relative to baseline and unrestricted eating; these findings support future studies examining TRE compliance and durability.

Original languageEnglish (US)
Article number1430
JournalNutrients
Volume13
Issue number5
DOIs
StatePublished - Apr 23 2021

Bibliographical note

Funding Information:
Funding: This work was supported by the Healthy Foods Healthy Lives program (17SFR-2YR50LC to LC), the National Institutes of Health (NIH National Center for Advancing Translational Sciences, UL1TR002494), NIH R01 DK118278 (PI Taub, SP is sub), and R01 AG065569 (PI: Blandine Laferrere, SP is sub).

Funding Information:
This work was supported by the Healthy Foods Healthy Lives program (17SFR2YR50LC to LC), the National Institutes of Health (NIH National Center for Advancing Translational Sciences, UL1TR002494), NIH R01 DK118278 (PI Taub, SP is sub), and R01 AG065569 (PI: Blandine Laferrere, SP is sub).

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

  • Quality of life
  • SF-36
  • Time-restricted eating

PubMed: MeSH publication types

  • Journal Article
  • Randomized Controlled Trial

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