Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: Possible mediation by endothelin

Keyphrases

• Thrombin 100%
• Endothelin 1 (ET-1) 100%
• Protease-activated Receptor 1 (PAR1) 70%
• Amides 50%
• Induced Behavior 20%
• Hyperalgesia 10%
• Abdominal 10%
• Spinal Cord 10%
• Nociception 10%
• Hippocampus 10%
• Signaling System 10%
• Astrocytes 10%
• Receptor Antagonist 10%
• N-methyl-D-aspartate Receptor (NMDAR) 10%
• Acid Activation 10%
• Hippocampal Neurons 10%
• Endothelin Receptor 10%
• Antihyperalgesic Effect 10%
• Selective Ligands 10%
• Pain Processing 10%
• Binding Site 10%
• Edema 10%
• Acetic Acid 10%
• Peptide Sequencing 10%
• Transient Effect 10%
• Receptor Activity 10%
• Thrombin Inhibition 10%
• Extracellular Protease 10%
• Mechanical Hyperalgesia 10%
• Natural Ligands 10%
• Hot Plate 10%
• Endothelin Receptor Antagonist 10%
• Von Frey 10%
• Potentiating Effect 10%
• BQ123 10%
• NMDA Antagonist 10%
• SLIGRL 10%
• Antithrombin Activity 10%
• NMDA Antagonism 10%
• Tethered Ligands 10%
• BQ-788 10%
• Protease-activated receptor-1 Antagonists 10%
• Endothelin B Receptor 10%
• 1 Receptor 10%
• Tail Latency 10%
• Evans Blue Extravasation 10%

Neuroscience

• N-Methyl-D-Aspartic Acid 100%
• Endothelin 100%
• Thrombin 100%
• Proteinase Activated Receptor 1 66%
• Carboxamide 41%
• Behavior (Neuroscience) 25%
• Receptor Antagonist 16%
• Hyperalgesia 16%
• Receptor 16%
• Spinal Cord 8%
• Hippocampus 8%
• Binding Site 8%
• Acetate 8%
• Protease-Activated Receptor 2 8%
• Agonist 8%
• Amino Acid Sequence 8%
• NMDA Receptor 8%
• Proteinase 8%
• BQ-123 8%
• Endothelin B Receptor 8%
• Endothelin A Receptor 8%
• Astrocyte 8%
• NMDA Receptor Antagonist 8%
• Nociception 8%
• Endothelin 1 8%
• BQ-788 8%