Thrombi within the urinary tract may serve as a nidus for rapid stone recurrence: A report of two cases

Ashley V Alford, Matthew Mocol, Michael S. Borofsky

Research output: Contribution to journalArticlepeer-review


Background: Nephrolithiasis is increasingly becoming one of the most prevalent and costly urologic conditions in the United States. The most common type of kidney stone in humans is calcium oxalate, accounting for 75% of idiopathic stones in first-time stone formers. Stone formation is typically a gradual process; however, certain factors can accelerate stone development and recurrence. Case Presentation: We present two cases of adult white men who were found to have rapidly recurrent symptomatic kidney stones that were ultimately determined to be comprised of an outer mineral shell with an inner core of blood clot. Both patients had a history of nephrolithiasis and recent hematuria. Urine supersaturation values at time of presentation supported formation of kidney stones. Conclusion: Thrombi within the urinary tract can serve as a nidus for formation of multiple types of kidney stones, including calcium oxalate and uric acid stones. Stones arising from such a nidus may exhibit unusually rapid growth.

Original languageEnglish (US)
Pages (from-to)425-427
Number of pages3
JournalJournal of Endourology Case Reports
Issue number4
StatePublished - 2020

Bibliographical note

Publisher Copyright:
© Mary Ann Liebert, Inc.


  • Recurrent stone disease
  • Urinary thrombi
  • Urolithiasis

PubMed: MeSH publication types

  • Case Reports


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