Three component coupling catalyzed by TaCl5-SiO2: Synthesis of α-amino phosphonates

S. Chandrasekhar, S. Jaya Prakash, V. Jagadeshwar, Ch Narsihmulu

Research output: Contribution to journalArticlepeer-review

249 Scopus citations

Abstract

TaCl5-SiO2 has been utilized as an efficient Lewis acid catalyst for the three component coupling of carbonyl compounds, aromatic amines and diethyl phosphite to produce α-amino phosphonates.

Original languageEnglish (US)
Pages (from-to)5561-5563
Number of pages3
JournalTetrahedron Letters
Volume42
Issue number32
DOIs
StatePublished - Aug 6 2001
Externally publishedYes

Bibliographical note

Funding Information:
Three of us (S.J.P., V.J. and C.N.) thank CSIR, New Delhi for financial support.

Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.

Keywords

  • Amine
  • Carbonyl compound
  • Diethyl phosphite
  • TaCl
  • α-amino phosphonate

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