Thermal Stabilization of Metal-Organic Framework-Derived Single-Site Catalytic Clusters through Nanocasting

Camille D. Malonzo, Sammy M. Shaker, Limin Ren, Steven D. Prinslow, Ana E. Platero-Prats, Leighanne C. Gallington, Joshua Borycz, Anthony B. Thompson, Timothy C. Wang, Omar K. Farha, Joseph T. Hupp, Connie C. Lu, Karena W. Chapman, Jason C. Myers, R. Lee Penn, Laura Gagliardi, Michael Tsapatsis, Andreas Stein

Research output: Contribution to journalArticlepeer-review

72 Scopus citations


Metal-organic frameworks (MOFs) provide convenient systems for organizing high concentrations of single catalytic sites derived from metallic or oxo-metallic nodes. However, high-temperature processes cause agglomeration of these nodes, so that the single-site character and catalytic activity are lost. In this work, we present a simple nanocasting approach to provide a thermally stable secondary scaffold for MOF-based catalytic single sites, preventing their aggregation even after exposure to air at 600°C. We describe the nanocasting of NU-1000, a MOF with 3 nm channels and Lewis-acidic oxozirconium clusters, with silica. By condensing tetramethylorthosilicate within the NU-1000 pores via a vapor-phase HCl treatment, a silica layer is created on the inner walls of NU-1000. This silica layer provides anchoring sites for the oxozirconium clusters in NU-1000 after the organic linkers are removed at high temperatures. Differential pair distribution functions obtained from synchrotron X-ray scattering confirmed that isolated oxozirconium clusters are maintained in the heated nanocast materials. Pyridine adsorption experiments and a glucose isomerization reaction demonstrate that the clusters remain accessible to reagents and maintain their acidic character and catalytic activity even after the nanocast materials have been heated to 500-600°C in air. Density functional theory calculations show a correlation between the Lewis acidity of the oxozirconium clusters and their catalytic activity. The ability to produce MOF-derived materials that retain their catalytic properties after exposure to high temperatures makes nanocasting a useful technique for obtaining single-site catalysts suitable for high-temperature reactions.

Original languageEnglish (US)
Pages (from-to)2739-2748
Number of pages10
JournalJournal of the American Chemical Society
Issue number8
StatePublished - Mar 2 2016

Bibliographical note

Funding Information:
This research was supported by the U.S. Department of Energy, Office of Basic Energy Sciences, Division of Chemical Sciences under Award DE-SC-0012702, except for the parts listed below. Parts of this work were carried out in the University of Minnesota Characterization Facility, which receives partial support from the NSF through the MRSEC, ERC, MRI, and NNIN programs. The sugar isomerization work was supported as part of the Catalysis Center for Energy Innovation, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Basic Energy Sciences under Award DE-SC0001004. Work done at Argonne was performed using the Advanced Photon Source, a U.S. Department of Energy (DOE) Office of Science User Facility operated for the DOE Office of Science by Argonne National Laboratory under Contract No. DE-AC02-06CH11357. A.E.P.P. acknowledges a Beatriu de Pino?s fellowship (BPDGR 2014) from the Ministry of Economy and Knowledge (Catalan Government). We thank Dr. Stephen Rudisill for obtaining SAED patterns.

Publisher Copyright:
© 2016 American Chemical Society.


Dive into the research topics of 'Thermal Stabilization of Metal-Organic Framework-Derived Single-Site Catalytic Clusters through Nanocasting'. Together they form a unique fingerprint.

Cite this