Thermal sensitivity in patients with diabetes mellitus

W. R. Kennedy, T. J. Fries, D. E.R. Sutherland

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Diabetic neuropathy affects peripheral somatic and autonomic nerves, the degree of involvement of each type of nerve fiber varying among patients. To gain understanding of the effects of the disease in a given patient it is therefore necessary to study several types of nerve fibers. Almost all of the diabetic patients who have been examined at the University of Minnesota for consideration of a pancreas transplantation (PTx) have had one or more of the secondary complications of the disease, ie, neuropathy, nephropathy, or retinopathy. Because the results of PTx on these complications is unknown, we have been studying nerve function in patients before and at intervals after PTx. For such a comparison to be valid, the evaluation of nerve function must be quantitative. We describe here the results of quantitative thermal sensitivity measured for 75 type I diabetic patients who presented for a PTx, and in 30 normal control subjects. None of the 40 patients studied before PTx have yet returned for post-PTx study, however 35 post-PTx patients who received their PTx before we began using thermal testing have been examined during a follow-up visit.

Original languageEnglish (US)
Pages (from-to)1775-1777
Number of pages3
JournalTransplantation proceedings
Volume18
Issue number6
StatePublished - 1986

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