There are many fevers: Communities’ perception and management of Febrile illness and its relationship with human animal interactions in South-Western Uganda

Michael Wandanje Mahero, Katey Pelican, Jacinta M. Waila, Shamilah Namusisi, Innocent B Rwego, Charles Kajura, Christopher Nyatuna, David R. Boulware, Joel Hartter, Lawrence Mugisha, Cheryl L Robertson, Dominic A Travis

Research output: Contribution to journalArticlepeer-review

Abstract

Diagnosing the causative agent of febrile illness in resource-limited countries is a challenge in part due to lack of adequate diagnostic infrastructure to confirm cause of infection. Most febrile illnesses (>60%) are non-malarial, with a significant proportion being zoonotic and likely from animal origins. To better characterize the pathways for zoonotic disease transmission and control in vulnerable communities, adequate information on the communities’ experiences and lexicon describing fever, and their understanding and perceptions of risk pathways is required. We undertook an ethnographic study to understand behaviors, exposures, and attitudes toward fever at the community level. Our hope is to better elucidate areas of priority surveillance and diagnostic investment. A focused ethnography consisting of participant observation, informal conversations, 4 barazas (community meetings), and formal ethnographic interviews (13 Focus group discussions and 17 Key informant interviews) was conducted between April and November 2015 in Kasese and Hoima Districts in Uganda. Perception of illness and associated risk factors was heavily influenced by the predominant livelihood activity of the community. The term “fever” referred to multiple temperature elevating disease processes, recognized as distinct pathological occurrences. However, malaria was the illness often cited, treated, or diagnosed both at the health facilities and through self-diagnosis and treatment. As expected, fever is as an important health challenge affecting all ages. Recognition of malarial fever was consistent with a biomedical model of disease while non-malarial fevers were interpreted mainly through ethno etiological models of explanation. These models are currently being used to inform education and prevention strategies and treatment regimens toward the goal of improving patients’ outcomes and confidence in the health system. Development of treatment algorithms that consider social, cultural, and economic contexts, especially where human-animal interaction is prevalent, should factor animal exposure and zoonotic illnesses as important differentials.

Original languageEnglish (US)
Article numbere0010125
JournalPLoS neglected tropical diseases
Volume16
Issue number2
DOIs
StatePublished - Feb 2022

Bibliographical note

Funding Information:
This project was funded through the NIH Fogarty Global Health Fellowship Award: R25TW009345 (https://www.fic.nih.gov/Programs/Pages/scholars-fellows-global-health.aspx) awarded to M.W.M. and a Discovery Grant IS-0001-08 from the Institute on the Environment (http://environment.umn.edu/), University of Minnesota awarded to K.M.P. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Publisher Copyright:
© 2022 Mahero et al.

PubMed: MeSH publication types

  • Journal Article
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

Fingerprint

Dive into the research topics of 'There are many fevers: Communities’ perception and management of Febrile illness and its relationship with human animal interactions in South-Western Uganda'. Together they form a unique fingerprint.

Cite this