Therapeutic Cytapheresis Using the Fenwal CS‐3000 Blood Cell Separator

Theresa A. Steeper, Judith A. Smith, Jeffrey McCullough

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Abstract. 20 patients, 16 with acute or chronic leukemia and 4 with thrombocytosis, underwent 47 therapeutic cytapheresis procedures using the Fenwal CS‐3000 cell separator. 16 of the 20 patients had acute clinical signs or symptoms secondary to high circulating cell counts; 14 showed symptomatic improvement following cytapheresis. An average of 2.0 whole blood volumes was processed per procedure. A mean white cell reduction of 64% and a mean platelet reduction of 53% were obtained per procedure on patients with leukemia and thrombocytosis, respectively. Hemoglobin levels decreased an average of 1.3 g/dl. Therapeutic cytapheresis procedures in which more than 1.5 blood volumes were processed did not result in significant additional cytoreduction.

Original languageEnglish (US)
Pages (from-to)193-200
Number of pages8
JournalVox Sanguinis
Volume48
Issue number4
DOIs
StatePublished - Apr 1985

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