Therapeutic approaches to non-Hodgkin's lymphoma in the elderly patient

Mary J. Ninan, Vicki A Morrison

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

The incidence of non-Hodgkin's lymphoma (NHL) is increasing among all age groups, with a median age at diagnosis of 67 years. With the increase in the geriatric population, there is a need for the development and validation of treatment strategies for NHL for these patients. Therapy in elderly patients is affected by multiple factors, especially comorbidities. Over the past decade, some treatment trials have included older patients. The disease incidence, characteristics and treatment approaches for both follicular and diffuse aggressive NHL histologies in elderly patients are reviewed, as well as the impact of aging on the care of these patients.

Original languageEnglish (US)
Pages (from-to)173-182
Number of pages10
JournalExpert Review of Hematology
Volume2
Issue number2
DOIs
StatePublished - Dec 1 2009

Keywords

  • Diffuse large-cell lymphoma
  • Elderly
  • Follicular lymphoma
  • NHL
  • Non-Hodgkins lymphoma
  • R-CHOP
  • Rituximab

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