Therapeutic angiogenesis is the use of angiogenic growth factors, genes that encode for growth factors, or cell-based therapies to enhance the natural process of collateral vessel development in ischemic tissue . The goal of therapeutic angiogenesis is to increase proangiogenic signals to alter the balance in favor of new blood vessel growth and vascular remodeling. This chapter reviews therapeutic agents used in myocardial angiogenesis, randomized placebo-controlled clinical trials in the field, and expectations for future research and therapy.
|Original language||English (US)|
|Title of host publication||Coronary Artery Disease|
|Subtitle of host publication||New Approaches without Traditional Revascularization|
|Number of pages||8|
|ISBN (Print)||1846284600, 9781846284601|
|State||Published - Apr 1 2012|