TheCellMap.org: A web-accessible database for visualizing and mining the global yeast genetic interaction network

Matej Usaj, Yizhao Tan, Wen Wang, Benjamin VanderSluis, Albert Zou, Chad L. Myers, Michael Costanzo, Brenda Andrews, Charles Boone

Research output: Contribution to journalArticlepeer-review

76 Scopus citations

Abstract

Providing access to quantitative genomic data is key to ensure large-scale data validation and promote new discoveries. TheCellMap.org serves as a central repository for storing and analyzing quantitative genetic interaction data produced by genome-scale Synthetic Genetic Array (SGA) experiments with the budding yeast Saccharomyces cerevisiae. In particular, TheCellMap.org allows users to easily access, visualize, explore, and functionally annotate genetic interactions, or to extract and reorganize subnetworks, using data-driven network layouts in an intuitive and interactive manner.

Original languageEnglish (US)
Pages (from-to)1539-1549
Number of pages11
JournalG3: Genes, Genomes, Genetics
Volume7
Issue number5
DOIs
StatePublished - May 1 2017

Bibliographical note

Publisher Copyright:
© 2017 Usaj et al.

Keywords

  • Genetic interactions
  • Genetic network
  • Synthetic genetic array SGA
  • Yeast genetics

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