The wheat Sr50 gene reveals rich diversity at a cereal disease resistance locus

Rohit Mago, Peng Zhang, Sonia Vautrin, Hana Šimková, Urmil Bansal, Ming Cheng Luo, Matthew Rouse, Haydar Karaoglu, Sambasivam Periyannan, James Kolmer, Yue Jin, Michael A. Ayliffe, Harbans Bariana, Robert F. Park, Robert McIntosh, Jaroslav Doležel, Hélène Bergès, Wolfgang Spielmeyer, Evans S. Lagudah, Jeff G. EllisPeter N. Dodds

Research output: Contribution to journalArticlepeer-review

68 Scopus citations

Abstract

We identify the wheat stem rust resistance gene Sr50 (using physical mapping, mutation and complementation) as homologous to barley Mla, encoding a coiled-coil nucleotide-binding leucine-rich repeat (CC-NB-LRR) protein. We show that Sr50 confers a unique resistance specificity different from Sr31 and other genes on rye chromosome 1RS, and is effective against the broadly virulent Ug99 race lineage. Extensive haplotype diversity at the rye Sr50 locus holds promise for mining effective resistance genes.

Original languageEnglish (US)
Article number15186
JournalNature plants
Volume1
DOIs
StatePublished - Nov 30 2015

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