The validity of a new practical quality of life measure in patients on renal replacement therapy

Areewan Cheawchanwattana, Chulaporn Limwattananon, Cynthia Gross, Supon Limwattananon, Viroj Tangcharoensathien, Cholatip Pongskul, Dhavee Sirivongs

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Objective: A new quality of life measure, a part of the National Health and Welfare 2003 survey, is a promising tool for outcome evaluation of clinical practice due to its brevity, validity, reliability, and providing easy interpretation against general population norm-based scores. The measure consisting of 9-items, and so called 9-item Thai Health status Assessment Instrument (9-THAI) was used to assess its validity and reliability in patients on renal replacement therapy (RRT). Material and Method: Three hundred and two patients on RRT who visited Srinagarind Hospital from March to May 2005 were studied. Convergent and divergent validity were assessed using SF-36 as the concurrent measure. Concurrent validity was also assessed using hematocrit level and hospitalization history in the last year as concurrent clinical measures. Test-retest reliability was studied by repeated measure within one month. Responsiveness of 9-THAI was studied in patients who reported health improvement. Results: Results of correlations between 9-THAI and SF-36 domains were as hypothesized. 9-THAI scores were significantly correlated with hematocrit level and hospitalization history. The results confirmed the validity of 9-THAI for use as a quality of life measure. Intraclass correlation coefficients of 9-THAI scores in stable patients were satisfactory. Among patients on RRT who reported overall health improvement, 9-THAI scores significantly increased, thus adding further evidence of the responsiveness of 9-THAI. Conclusion: The 9-THAI is a valid and reliable generic health status measure that can be used as an ideal core in a battery of quality of life measures in clinical practice for patients on RRT.

Original languageEnglish (US)
Pages (from-to)S207-S217
JournalJournal of the Medical Association of Thailand
Issue numberSUPPL. 2
StatePublished - Aug 2006

Bibliographical note

Copyright 2008 Elsevier B.V., All rights reserved.


  • Generic health status measure
  • Health-related quality of life
  • Quality of life
  • Reliability
  • Renal replacement therapy
  • Responsiveness
  • SF-36
  • Validity


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