The utility of genomic prediction models in evolutionary genetics

Research output: Contribution to journalArticle

5 Scopus citations


Variation in complex traits is the result of contributions from many loci of small effect. Based on this principle, genomic prediction methods are used to make predictions of breeding value for an individual using genome-wide molecular markers. In breeding, genomic prediction models have been used in plant and animal breeding for almost two decades to increase rates of genetic improvement and reduce the length of artificial selection experiments. However, evolutionary genomics studies have been slow to incorporate this technique to select individuals for breeding in a conservation context or to learn more about the genetic architecture of traits, the genetic value of missing individuals or microevolution of breeding values. Here, we outline the utility of genomic prediction and provide an overview of the methodology. We highlight opportunities to apply genomic prediction in evolutionary genetics of wild populations and the best practices when using these methods on field-collected phenotypes.

Original languageEnglish (US)
Article number20210693
JournalProceedings of the Royal Society B: Biological Sciences
Issue number1956
StatePublished - Aug 11 2021

Bibliographical note

Funding Information:
Funding. S.M. was supported by the National Science Foundation IOS-1546727, NSF EDGE Award IOS-1923372 and NIH 1R01GM127872-01 during the writing of this manuscript.

Publisher Copyright:
© 2021 The Author(s).


  • BLUP
  • breeding value
  • quantitative genetics

PubMed: MeSH publication types

  • Journal Article
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.


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