The utility and cross-validation of a composite physical activity score in relation to cardiovascular health indicators: Coronary artery risk development in young adults

Kelley Pettee Gabriel, Adriana Pérez, David R. Jacobs, Joowon Lee, Harold W. Kohl, Barbara Sternfeld

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Background: Single-method assessment of physical activity (PA) has limitations. The utility and cross-validation of a composite PA score that includes reported and accelerometer-derived PA data has not been evaluated. Methods: Participants attending the Year 20 exam were randomly assigned to the derivation (two-thirds) or validation (one-third) data set. Principal components analysis was used to create a composite score reflecting Year 20 combined reported and accelerometer PA data. Generalized linear regression models were constructed to estimate the variability explained (R2) by each PA assessment strategy (self-report only, accelerometer only, composite score, or self-report plus accelerometer) with cardiovascular health indicators. This process was repeated in the validation set to determine cross-validation. Results: At Year 20, 3549 participants (45.2 [3.6] y, 56.7% female, and 53.5% black) attended the clinic exam and 2540 agreed to wear the accelerometer. Higher R2 values were obtained when combined assessment strategies were used; however, the approach yielding the highest R2 value varied by cardiovascular health outcome. Findings from the cross-validation also supported internal study validity. Conclusions: Findings support continued refinement of methodological approaches to combine data from multiple sources to create a more robust estimate that reflects the complexities of PA behavior.

Original languageEnglish (US)
Pages (from-to)847-856
Number of pages10
JournalJournal of Physical Activity and Health
Volume15
Issue number11
DOIs
StatePublished - Nov 2018

Bibliographical note

Funding Information:
The authors would like to acknowledge the Coronary Artery Risk Development in Young Adults Study (CARDIA) participants. The CARDIA is supported by contracts HHSN268201300025C, HHSN268201300026C, HHSN268201300027C, HHSN268201300028C, HHSN268201300029C, and HHSN268200900041C from the National Heart, Lung, and Blood Institute (NHLBI), the Intramural Research Program of the National Institute on Aging (NIA), and an intra-agency agreement between NIA and NHLBI (AG0005). This study was also supported by the American Heart Association—Southwest Affiliate—Beginning Grant in Aid Award 14BGIA18520004 (to K.P.G.).

Publisher Copyright:
© 2018 Human Kinetics, Inc.

Keywords

  • Physical activity assessmentepidemiologybiostatistics

Fingerprint

Dive into the research topics of 'The utility and cross-validation of a composite physical activity score in relation to cardiovascular health indicators: Coronary artery risk development in young adults'. Together they form a unique fingerprint.

Cite this